Cellular Networks

Research Areas

Cellular Networks

Despite major advances, our understanding of the molecular networks that control cell function, and the way in which dysregulation of these networks promotes disease, remains far from complete.

Developing avenues for new therapies and diagnostic tests relies on our comprehension of the molecular mechanisms regulating the progress of disease. A Systems Biology approach to studying disease progression is to construct network models from high-quality molecular data, and to interrogate these networks through computational analysis.

We are combining novel methods developed at the Systems Biology Laboratory with other techniques for network-based analysis, and applying this approach to datasets in a variety of disease types to uncover potential targets for further investigation. We are also integrating clinical information such as patient history, survival and age, with molecular data to improve the predictive power and clinical applicability of this approach.