After graduating with a BSc (Hons) in Physics from Imperial College London, Edmund completed a DPhil in Applied Mathematics at the University of Oxford. He was subsequently elected to a Junior Research Fellowship at Brasenose College Oxford and in 2001 he won a Research Fellowship from the Wellcome Trust to study mathematical models of heart disease. In 2003 Edmund moved to the University of Auckland to continue this work at the Auckland Bioengineering Institute, where he established the Systems Biology group. Edmund moved to the University of Melbourne in 2013 to take up the Chair of Systems and Computational Biology.
Edmund’s research uses mathematical and computer modelling to investigate regulatory processes and pathways underlying complex human diseases. A feature of his group’s research is to include cell and tissue structural information in models of the biochemical networks that control cell function. Current research projects include using mathematical models of heart cells to understand the development of heart disease; developing computational models to study the network of genetic interactions underlying breast and skin cancers; and modelling the regulation of fluid secretion in the salivary glands and the lungs.